Interactions between ICAM-5 and b1 integrins regulate neuronal synapse formation
نویسندگان
چکیده
Lin Ning, Li Tian, Sergei Smirnov, Helena Vihinen, Olaya Llano, Kyle Vick, Ronald L. Davis, Claudio Rivera and Carl G. Gahmberg* Division of Biochemistry and Biotechnology, Faculty of Biological and Environmental Sciences, University of Helsinki, Finland Neuroscience Center, University of Helsinki, Finland Institute of Biotechnology, University of Helsinki, Finland Department of Neuroscience, Scripps Research Institute Florida, Jupiter, FL 33410, USA
منابع مشابه
Interactions between ICAM-5 and β1 integrins regulate neuronal synapse formation.
Intercellular adhesion molecule-5 (ICAM-5) is a dendrite-specific adhesion molecule, which functions in both the immune and nervous systems. ICAM-5 is the only negative regulator that has been identified for maturation of dendritic spines so far. Shedding of the ICAM-5 ectodomain promotes spine maturation and enhances synaptic activity. However, the mechanism by which ICAM-5 regulates spine dev...
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